Top: Somatic duplication found in the PSEN2 gene on chromosome 1 of the HCC1395 cell line. Bottom: This duplication was found using a novel deep learning-based structural variant caller. Courtesy Hajirasouliha Lab.
Doctoral Program
Physiology, Biophysics & Systems Biology
Top: The breakpoint proximity curve BPpc adjusted by its expected values using multiple tissue-specific breakpoint covariates in a generalized additive model (GAM). Bottom: Partial contribution of the interaction of TAD and gene density as a genomic covariate to predict the expected breakpoint proximity curve. Courtesy Khurana Lab.
