Immune compartments at the brain’s borders in health and neurovascular diseases

Publication Type Article
Authors Goertz, J.E., Garcia-Bonilla, L., ladecola, C., Anrather, J.
Journal Seminars in Immunopathology
Volume 45
Pagination 437-449
Date Published 05/03/2023
Abstract

Recent evidence implicates cranial border immune compartments in the meninges, choroid plexus, circumventricular organs, and skull bone marrow in several neuroinflammatory and neoplastic diseases. Their pathogenic importance has also been described for cardiovascular diseases such as hypertension and stroke. In this review, we will examine the cellular composition of these cranial border immune niches, the potential pathways through which they might interact, and the evidence linking them to cardiovascular disease.

DOI 10.1007/s00281-023-00992-6
PubMed ID 37138042
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