Sarah Kane is a Senior Genetic Counselor at Memorial Sloan Kettering Cancer Center (MSKCC) with over 11 years of experience in clinical cancer genetic counseling. Sarah graduated from the Boston University School of Medicine Genetic Counseling program in 2015. Prior to joining MSKCC, Sarah was an adult and pediatric cancer genetic counselor at Dana Farber Cancer Institute. During her career, Sarah has provided clinical supervision and research mentorship to M.S Genetic Counseling students from various training programs. Sarah’s clinical expertise is focused on hereditary gastrointestinal cancer syndromes, such as Lynch syndrome and hereditary polyposis conditions, and on the integration of tumor-normal sequencing into routine clinical care for patients with cancer.
Selected Publications:
O'Connor CA, Harrold E, Lin D, Walch H, Gazzo A, Ranganathan M, Kane S, Keane F, Schoenfeld J, Moss D, Thurtle-Schmidt DM, Suehnholz SP, Chakravarty D, Balogun F, Varghese A, Yu K, Kelsen D, Latham A, Weigelt B, Park W, Stadler Z, O'Reilly EM. Lynch Syndrome and Somatic Mismatch Repair Variants in Pancreas Cancer. JAMA Oncol. 2024 Nov 1;10(11):1511-1518. doi: 10.1001/jamaoncol.2024.3651. PMID: 39235819; PMCID: PMC11378065.
Sia TY, Moufarrij S, Milani J, Kane S, Zhou Q, Fong C, Khurram A, Kemel YM, Sheehan M, Latham A, Carlo MI, Murciano-Goroff YR, Banaszak LG, Abbass M, Offit K, Iasonos A, Roche KL, Chi DS, Mandelker D, Aghajanian C, Abu-Rustum NR, Stadler ZK, Tew WP, Lichtman SM, Liu YL. Germline landscape of high grade serous ovarian cancer across age groups: Is age just a number?Gynecol Oncol. 2025 Oct;201:60-68. doi: 10.1016/j.ygyno.2025.08.016. Epub 2025 Aug 13. PMID: 40812120; PMCID: PMC12418476.
Ranganathan M, Sacca RE, Trottier M, Maio A, Kemel Y, Salo-Mullen E, Catchings A, Kane S, Wang C, Ravichandran V, Ptashkin R, Mehta N, Garcia-Aguilar J, Weiser MR, Donoghue MTA, Berger MF, Mandelker D, Walsh MF, Carlo M, Liu YL, Cercek A, Yaeger R, Saltz L, Segal NH, Mendelsohn RB, Markowitz AJ, Offit K, Shia J, Stadler ZK, Latham A. Prevalence and Clinical Implications of Mismatch Repair-Proficient Colorectal Cancer in Patients With Lynch Syndrome. JCO Precis Oncol. 2023 May;7:e2200675. doi: 10.1200/PO.22.00675. PMID: 37262391; PMCID: PMC10309569.
