We investigate how sphingolipid metabolism and signaling regulate vascular and cardiac function, aiming to uncover mechanisms driving cardiometabolic disease and identify therapeutic targets to improve cardiovascular health.
My laboratory investigates molecular mechanisms regulating sphingolipid metabolism and signaling in blood vessels and the heart, in both health and disease. Our work has uncovered novel pathways controlling sphingolipid biosynthesis and how its dysregulation contributes to cardiometabolic disorders. We have published extensively in leading journals, including Nature Medicine, Nature Communications, and Circulation Research. I am deeply committed to mentorship and have trained PhD students and postdoctoral fellows who now hold positions in academia as well as in the biotechnology and pharmaceutical industries.
Biography
I am Professor of Pathology and Laboratory Medicine, Pharmacology, and Cell and Developmental Biology at Weill Cornell Medicine, where I previously served as Associate and Assistant Professor. Prior to joining Weill Cornell, I was an Associate Research Scientist at Yale School of Medicine, following postdoctoral training there. I earned my PhD in Pharmacology from the University of Naples Federico II. My research focuses on sphingolipid metabolism and signaling in cardiovascular biology, building on a strong foundation in vascular biology to lead an independent program investigating mechanisms of cardiometabolic disease.
